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Bora Acquires Pyros Pharmaceuticals to Bolster Upsher-Smith Rare Disease Product Portfolio

Upsher-Smith Expands Ongoing Partnership with Appco

Adds New Pipeline Product to its Portfolio

Maple Grove, MN – September 12, 2022 — Upsher-Smith Laboratories, LLC (Upsher-Smith) today announced that it has expanded its ongoing partnership with Appco Pharma LLC (Appco) with the addition of a near-term generic product opportunity to its portfolio. This collaboration is part of Upsher-Smith’s company-wide effort to grow the Company’s portfolio of products through strategic partnerships and product acquisitions.

“This agreement further expands an already solid working relationship between Upsher-Smith and Appco,” said Rich Fisher, President and COO, Upsher-Smith. “Appco has extensive skills and experience in the development of diverse dosage forms that span a wide range of therapeutic areas. Our long-standing partnership has yielded a number of commercial-stage products. We are pleased to add their development strengths to our core competencies and expand Upsher-Smith’s product portfolio to accelerate growth in the U.S.”

“We are pleased to add one more product to our partnership with Upsher-Smith,” said Srini Paruchuri, COO, Appco. “Appco highly values Upsher-Smith’s strength in sales and marketing which complements Appco’s development and manufacturing capabilities. We look forward to expanding and growing this partnership.’’

Upsher-Smith will open its world-class manufacturing facility in Maple Grove, MN later this year. The new, 270,000 square foot facility will have fully up-to-date serialization and packaging capabilities and has capacity and capabilities that can support contract manufacturing for third parties. To learn more, visit www.upsher-smith.com.

About Upsher-Smith

Upsher-Smith Laboratories, LLC is a trusted U.S. pharmaceutical company that strives to improve the health and lives of patients through an unwavering commitment to high-quality products and sustainable growth. The company brings brands and generics to a wide array of customers, always backed by its attentive level of service, strong industry relationships, and dedication to consistent product supply. For more information, visit www.upsher-smith.com.

About Appco

Established in 2012, Appco Pharma LLC is a New Jersey-based generic drug development and manufacturing company. It operates through U.S. FDA-approved manufacturing sites in Piscataway NJ. The Appco team has extensive skills and experience in the development of complex drugs including dosage forms like tablets, capsules, extended-release formulations, oral liquids and suspensions. For more information, visit www.appcopharma.com.

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